rs4880, SOD2

N. diseases: 131
Disease: Coronary heart disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE Association between the rs4880 superoxide dismutase 2 (C>T) gene variant and coronary heart disease in diabetes mellitus. 20728955 2010
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE Association of C47T polymorphism in SOD2 gene with coronary artery disease: a case-control study and a meta-analysis. 22170599 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 years old), determined their genotypes regarding glutamate-cysteine ligase modifier subunit (GCLM) C-588T, manganese superoxide dismutase (SOD2) Val16Ala, endothelial nitric oxide synthase (NOS3) G894T, NAD(P)H oxidase p22phox (CYBA) C242T, and myeloperoxidase (MPO) G-463A polymorphisms, and prospectively evaluated the association between these polymorphisms and CHD events. 24933031 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE However, they suggest that Ala16Val MnSOD polymorphism and decreased antioxidant defences are likely contributed to CHD risk in Tunisian men. 27067415 2016