rs4880, SOD2

N. diseases: 131
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE However, they suggest that Ala16Val MnSOD polymorphism and decreased antioxidant defences are likely contributed to CHD risk in Tunisian men. 27067415 2016
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 years old), determined their genotypes regarding glutamate-cysteine ligase modifier subunit (GCLM) C-588T, manganese superoxide dismutase (SOD2) Val16Ala, endothelial nitric oxide synthase (NOS3) G894T, NAD(P)H oxidase p22phox (CYBA) C242T, and myeloperoxidase (MPO) G-463A polymorphisms, and prospectively evaluated the association between these polymorphisms and CHD events. 24933031 2014
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE Association of C47T polymorphism in SOD2 gene with coronary artery disease: a case-control study and a meta-analysis. 22170599 2012
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.040 GeneticVariation BEFREE Association between the rs4880 superoxide dismutase 2 (C>T) gene variant and coronary heart disease in diabetes mellitus. 20728955 2010