rs4880, SOD2

N. diseases: 131
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.050 GeneticVariation BEFREE Clinical variables and ethnicity may influenced by polymorphism of CAT -262C/T and MnSOD 47C/T antioxidant enzymes in Algerian type1 diabetes without complications. 29859283 2018
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.050 GeneticVariation BEFREE Regression analysis showed that TT genotype of SOD2 Val16Ala conferred significantly lower ESRD risk among patients without diabetes (odds ratio 0.699; p = 0.018).GPX1 SNP alone did not alter the risk. 26881045 2016
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.050 GeneticVariation BEFREE Association between the rs4880 superoxide dismutase 2 (C>T) gene variant and coronary heart disease in diabetes mellitus. 20728955 2010
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.050 GeneticVariation BEFREE In conclusion, our results suggest that V16A polymorphism of the Mn-SOD gene is not related to the development of diabetes and progression of DR, but is associated with DME in Korean type 2 diabetic patients. 17142144 2006
Diabetes Mellitus
CUI: C0011849
Disease: Diabetes Mellitus
0.050 GeneticVariation BEFREE These results suggest that V16A polymorphism of Mn-SOD gene is not related to pathogenesis of diabetes but is associated with stages of albuminuria in Korean type 2 diabetes. 16324912 2006