Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our study suggests that rs4880 and rs4244285 polymorphisms play an important role in development of breast cancer in an Iraqi population, and no significant association was found between rs1801274 and the risk of breast cancer.
|
29482947 |
2018 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our study suggests that rs4880 and rs4244285 polymorphisms play an important role in development of breast cancer in an Iraqi population, and no significant association was found between rs1801274 and the risk of breast cancer.
|
29482947 |
2018 |
Malignant neoplasm of prostate
|
|
0.100 |
GeneticVariation
|
BEFREE |
Previous studies have investigated the relationship between manganese superoxide dismutase (MnSOD) Val16Ala polymorphism and prostate cancer susceptibility, but the results have remained controversial.
|
27055786 |
2016 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Here, we investigated the effect of MnSOD (p.Val16Ala, rs4880) and CAT (-262C>T, rs1001179) SNPs on the association between the MD and BC risk in the case-control study of BC MASTOS in Cyprus.
|
26130326 |
2016 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Here, we investigated the effect of MnSOD (p.Val16Ala, rs4880) and CAT (-262C>T, rs1001179) SNPs on the association between the MD and BC risk in the case-control study of BC MASTOS in Cyprus.
|
26130326 |
2016 |
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Previous studies have investigated the relationship between manganese superoxide dismutase (MnSOD) Val16Ala polymorphism and prostate cancer susceptibility, but the results have remained controversial.
|
27055786 |
2016 |
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Among patients who underwent RT in the test cohort, there was a significant association between 3 of the 7 SOD2 SNPs and lethal prostate cancer: rs6917589 (overall P = .006), rs2758331 (P = .04) and the functional valine to alanine polymorphism in rs4880 (P = .04).
|
25662905 |
2015 |
Malignant neoplasm of prostate
|
|
0.100 |
GeneticVariation
|
BEFREE |
Among patients who underwent RT in the test cohort, there was a significant association between 3 of the 7 SOD2 SNPs and lethal prostate cancer: rs6917589 (overall P = .006), rs2758331 (P = .04) and the functional valine to alanine polymorphism in rs4880 (P = .04).
|
25662905 |
2015 |
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Here, we performed integrated in vivo and in vitro protocols that analyzed the association between Ala16Val-SOD2 polymorphism and prostate cancer aggressiveness at the time of diagnosis and evaluated the effect of the imbalance on PC proliferation using the DU-145 PC cell line treated with paraquat and porphyrin.
|
26468117 |
2015 |
Malignant neoplasm of prostate
|
|
0.100 |
GeneticVariation
|
BEFREE |
Here, we performed integrated in vivo and in vitro protocols that analyzed the association between Ala16Val-SOD2 polymorphism and prostate cancer aggressiveness at the time of diagnosis and evaluated the effect of the imbalance on PC proliferation using the DU-145 PC cell line treated with paraquat and porphyrin.
|
26468117 |
2015 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
A polymorphism in its encoding gene (SOD2: Val16Ala rs4880) may confer poorer breast cancer survival, but data are inconsistent.
|
24498107 |
2014 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
The overall survival (OS), breast cancer-specific survival (BCSS), and relapse-free survival (RFS), assessed by using Kaplan-Meier survival analysis and multivariate Cox regression analysis, were evaluated according to the adjuvant treatments and the rs4880 and rs13181 genotypes.
|
24716840 |
2014 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
A polymorphism in its encoding gene (SOD2: Val16Ala rs4880) may confer poorer breast cancer survival, but data are inconsistent.
|
24498107 |
2014 |
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In the present study we investigated the association of a number of polymorphic changes in antioxidant system genes (SNPs rs1050450 in the GPX1 gene, rs1695 and rs1138272 in the GSTP1 gene and rs4880 in the MnSOD gene) with the risk of prostate cancer.
|
24610081 |
2014 |
Malignant neoplasm of prostate
|
|
0.100 |
GeneticVariation
|
BEFREE |
In the present study we investigated the association of a number of polymorphic changes in antioxidant system genes (SNPs rs1050450 in the GPX1 gene, rs1695 and rs1138272 in the GSTP1 gene and rs4880 in the MnSOD gene) with the risk of prostate cancer.
|
24610081 |
2014 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The overall survival (OS), breast cancer-specific survival (BCSS), and relapse-free survival (RFS), assessed by using Kaplan-Meier survival analysis and multivariate Cox regression analysis, were evaluated according to the adjuvant treatments and the rs4880 and rs13181 genotypes.
|
24716840 |
2014 |
Malignant neoplasm of prostate
|
|
0.100 |
GeneticVariation
|
BEFREE |
Statistically significant effect modification of both HCA (DiMeIQx) and darkly browned meat intake and PCa risk was observed for allelic variants of MnSOD (rs4880) (P(interaction): 0.02).
|
22564066 |
2012 |
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Statistically significant effect modification of both HCA (DiMeIQx) and darkly browned meat intake and PCa risk was observed for allelic variants of MnSOD (rs4880) (P(interaction): 0.02).
|
22564066 |
2012 |
Malignant neoplasm of prostate
|
|
0.100 |
GeneticVariation
|
BEFREE |
We previously reported a statistically significant interaction between circulating selenium levels, variants in the superoxide dismutase 2 gene (SOD2; rs4880), and risk of developing prostate cancer and presenting with aggressive prostate cancer.
|
20477822 |
2011 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our results suggest that MnSOD 47T>C polymorphism in interaction with long-term HRT use may modify the risk of breast cancer.
|
21567099 |
2011 |
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We previously reported a statistically significant interaction between circulating selenium levels, variants in the superoxide dismutase 2 gene (SOD2; rs4880), and risk of developing prostate cancer and presenting with aggressive prostate cancer.
|
20477822 |
2011 |
Prostate carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
A high tertile selenium level in combination with non-wt rs125701 of the OGG1 gene in combination with smoking status or rs4880 related variation of MnSOD gene appeared to protect from PrCa.
|
21982398 |
2011 |
Malignant neoplasm of prostate
|
|
0.100 |
GeneticVariation
|
BEFREE |
A high tertile selenium level in combination with non-wt rs125701 of the OGG1 gene in combination with smoking status or rs4880 related variation of MnSOD gene appeared to protect from PrCa.
|
21982398 |
2011 |
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our results suggest that MnSOD 47T>C polymorphism in interaction with long-term HRT use may modify the risk of breast cancer.
|
21567099 |
2011 |
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Polymorphism (ALA16VAL) correlates with regional lymph node status in breast cancer.
|
20082851 |
2010 |