rs4986790, TLR4

N. diseases: 223
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Acute pancreatitis
CUI: C0001339
Disease: Acute pancreatitis
0.030 GeneticVariation BEFREE Our current meta-analysis suggests that TLR4 Asp299Gly and Thr399Ile polymorphisms may not be risk factors to AP susceptibility. 24914392 2014
Acute pancreatitis
CUI: C0001339
Disease: Acute pancreatitis
0.030 GeneticVariation BEFREE In view of the inflammatory nature of acute pancreatitis, we aimed to determine the predictive value of two point mutations in the promoter region at position -550 (H/L variants) and -221 (X/Y variants) of the MBL2 gene, and the Asp299Gly and 119C>A polymorphisms of the TLR4 gene on the occurrence of severe acute pancreatitis (SAP). 18288881 2008
Acute pancreatitis
CUI: C0001339
Disease: Acute pancreatitis
0.030 GeneticVariation BEFREE Toll-like receptor 4 Asp299Gly polymorphism is associated with the infection of pancreatic necrosis in AP. 17414051 2007