rs4986790, TLR4

N. diseases: 223
Disease: Bacterial Infections ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Bacterial Infections
CUI: C0004623
Disease: Bacterial Infections
0.030 GeneticVariation BEFREE Toll-like receptor 4 D299G polymorphism could influence not only the predisposition to bacterial infections but also the evolution of the disease in cirrhotic patients. 20222908 2010
Bacterial Infections
CUI: C0004623
Disease: Bacterial Infections
0.030 GeneticVariation BEFREE Two single nucleotide polymorphisms (SNPs) encoding Asp299Gly and Thr399Ile substitutions in the TLR4 ectodomain were previously associated with TLR4 hyporesponsiveness and increased susceptibility to bacterial infection. 17709532 2007
Bacterial Infections
CUI: C0004623
Disease: Bacterial Infections
0.030 GeneticVariation BEFREE Polymorphisms in TLR2 (Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes are associated with bacterial infections, we therefore studied these polymorphisms in osteomyelitis patients. 16487238 2006