rs4986790, TLR4

N. diseases: 223
Disease: Bronchiolitis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Bronchiolitis
CUI: C0006271
Disease: Bronchiolitis
0.030 GeneticVariation BEFREE The aim was to study the association between the TLR4 Asp299Gly polymorphism and the susceptibility to severe RSV bronchiolitis in infants. 20575099 2010
Bronchiolitis
CUI: C0006271
Disease: Bronchiolitis
0.030 GeneticVariation BEFREE The presence of TLR4 mutations (Asp299Gly and Thr399Ile) were associated with severe RSV bronchiolitis and were significantly over-represented in groups II and III. 16542364 2006
Bronchiolitis
CUI: C0006271
Disease: Bronchiolitis
0.030 GeneticVariation BEFREE Each of the TLR4 mutations, either alone or in cosegregation, were associated with severe RSV bronchiolitis: the Asp299Gly and Thr399Ile mutations were significantly overrepresented in group I, compared with groups II and III. 15143473 2004