rs4986790, TLR4

N. diseases: 146
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.040 GeneticVariation BEFREE Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. 15632890 2005
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.040 GeneticVariation BEFREE We studied the TLR4 gene Asp299Gly polymorphism in relation to susceptibility to myocardial infarction in a cohort of patients with angiographically documented coronary artery disease, and performed a meta-analysis using data sets from three independent studies. 15864121 2005
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.040 GeneticVariation BEFREE The findings of this study do not support the hypothesis that the TLR4 Asp299Gly polymorphism influences predisposition to and progression of coronary artery disease. 12957699 2004
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.040 GeneticVariation BEFREE Among symptomatic men with documented coronary artery disease, the TLR4 Asp299Gly polymorphism was associated with the risk of cardiovascular events. 12742999 2003