rs4986790, TLR4

N. diseases: 146
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.060 GeneticVariation BEFREE The TLR4/Asp299Gly and CD14/C-260T polymorphisms and plasma sCD14 concentrations do not appear as significant predictors of the risk of CHD in healthy individuals. 15367917 2005
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.060 GeneticVariation BEFREE A polymorphism of the TLR4 gene, Asp299Gly, is associated with an increased risk for coronary heart diseases in Caucasian populations. 15910856 2005
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.060 GeneticVariation BEFREE Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. 15632890 2005
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.060 GeneticVariation BEFREE We studied the TLR4 gene Asp299Gly polymorphism in relation to susceptibility to myocardial infarction in a cohort of patients with angiographically documented coronary artery disease, and performed a meta-analysis using data sets from three independent studies. 15864121 2005
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.060 GeneticVariation BEFREE The findings of this study do not support the hypothesis that the TLR4 Asp299Gly polymorphism influences predisposition to and progression of coronary artery disease. 12957699 2004
Coronary heart disease
CUI: C0010068
Disease: Coronary heart disease
0.060 GeneticVariation BEFREE Among symptomatic men with documented coronary artery disease, the TLR4 Asp299Gly polymorphism was associated with the risk of cardiovascular events. 12742999 2003