rs4986790, TLR4

N. diseases: 223
Disease: Hepatitis B ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.040 GeneticVariation BEFREE The TLR4 rs4986790 minor G genotype was linked with significantly increased risk for HBV/HCV chronic infection (P < 0.001). 30421643 2019
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.040 GeneticVariation BEFREE The results showed a lack of association between the rs4986790 and rs4986791 SNPs and susceptibility to infection with HBV and HCV, as well as clinical and laboratory information of the patients. 26347404 2015
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.040 GeneticVariation BEFREE In conclusion, in HBV-positive Caucasian patients, the A/A genotype of the rs4986790 polymorphism may influence a worse outcome of chronic HBV infection, mainly through a synergistic interaction with male gender. 23093310 2013
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.040 GeneticVariation BEFREE Toll-like receptor 4 rs4986790 (p.Asp299Gly) was associated with HBsAg seroclearance/seroconversion in chronic HBV patients. 22740716 2012