rs4986790, TLR4

N. diseases: 223
Disease: Giant Cell Arteritis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Giant Cell Arteritis
CUI: C0039483
Disease: Giant Cell Arteritis
0.030 GeneticVariation BEFREE A meta-analysis, comprising 577 GCA patients and 1153 controls, did not confirm an association between GCA and rs4986790 (OR 1.29, 95% CI 0.86, 1.92, p=0.22). 24447403 2014
Giant Cell Arteritis
CUI: C0039483
Disease: Giant Cell Arteritis
0.030 GeneticVariation BEFREE This meta-analysis demonstrates that the TLR4 Asp299Gly polymorphism may confer susceptibility to GCA. 23065292 2013
Giant Cell Arteritis
CUI: C0039483
Disease: Giant Cell Arteritis
0.030 GeneticVariation BEFREE A total of 155 patients with biopsy-proven GCA who were residents of Reggio Emilia, Italy, and 210 population-based controls from the same geographical area were genotyped for two coding single nucleotide polymorphisms of TLR4 (Asp299Gly and Thr399Ile) by molecular methods. 19646345 2010