rs4986790, TLR4

N. diseases: 146
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.040 GeneticVariation BEFREE In conclusion, our data suggest that TLR4 (D299G and T399I) and TNF (-308G/A) genetic polymorphisms may influence the risk of developing tuberculosis after exposure to Mycobacterium. 26774366 2016
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.040 GeneticVariation BEFREE Lack of association between Toll-like receptor 4 gene Asp299Gly and Thr399Ile polymorphisms and tuberculosis susceptibility: a meta-analysis. 23200920 2013
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.040 GeneticVariation BEFREE The toll-like receptor 4 Asp299Gly variant and tuberculosis susceptibility in HIV-infected patients in Tanzania. 17545720 2007
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.040 GeneticVariation BEFREE Our data suggest that TLR4 Asp299Gly has no influence on monocyte LPS responses or susceptibility to TB in Gambians and could be an ancient neutral polymorphism. 15525557 2005