rs4986790, TLR4
N. diseases: 223
Source: ALL
Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year |
---|---|---|---|---|---|---|---|
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
|
0.060 | GeneticVariation | BEFREE | Altered Th17 Cytokine Expression in Helicobacter pylori Patients with TLR4 (D299G) Polymorphism. | 26853914 | 2016 | |
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
|
0.060 | GeneticVariation | BEFREE | The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the pathogenesis of Helicobacter pylori related gastroduodenal diseases in relation to gastric secretion and inflammation. | 26161647 | 2015 | |
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
|
0.060 | GeneticVariation | BEFREE | However, we detected that A allele carriers of the TLR4 Asp299Gly polymorphism might have an increase risk of gastric cancer in the Helicobacter pylori-positive population (G allele vs. A allele: OR=2.01, 95%CI: 1.22, 3.31). | 24007538 | 2013 | |
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
|
0.060 | GeneticVariation | BEFREE | There was no association between TLR4 Asp299Gly polymorphism and any type of lesions, except for a slight nonsignificant increase in risk of IM associated with the AA genotype among subjects with a higher histological HP score. | 17171451 | 2007 | |
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
|
0.060 | GeneticVariation | BEFREE | A Toll-like receptor-4 (TLR-4) Asp299Gly and Thr399Ileu substitution reduces responsiveness to Helicobacter pylori (H. pylori) lipopolysaccharide. | 18082569 | 2007 | |
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
|
0.060 | GeneticVariation | BEFREE | We genotyped 87 patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma, 594 Helicobacter pylori positive controls and 358 healthy blood donors to investigate an association of TLR4 Asp299Gly in the development of gastric MALT lymphoma. | 16019531 | 2005 |