Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
0.070 GeneticVariation BEFREE The aim of this study was to investigate the possible role of polymorphisms of TLR4, Asp299Gly and Thr399Ile and CD14, C-159T and C-550T in the development of RSV bronchiolitis. 25572736 2015
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
0.070 GeneticVariation BEFREE TLR4 Asp299Gly and Thr399Ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virus. 20711470 2010
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
0.070 GeneticVariation BEFREE Toll-like receptor 4 Asp299Gly polymorphism in respiratory syncytial virus epidemics. 20575099 2010
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
0.070 GeneticVariation BEFREE Both SNPs were highly associated with symptomatic RSV disease in this largely premature population (p < 0.0001), with 89.5% and 87.6% of cases being heterozygous for Asp299Gly and Thr399Ile polymorphisms versus published control frequencies of 10.5% and 6.5%, respectively. 17709532 2007
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
0.070 GeneticVariation BEFREE By genotyping 236 children with RSV infection and 219 healthy controls we found no association between the risk of severe RSV infection and Asp299Gly polymorphisms (P>0.05), and we demonstrate that the TLR4 Asp299Gly genotype does not influence susceptibility to either RSV serotype A or B (P>0.05). 17449325 2007
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
0.070 GeneticVariation BEFREE The presence of TLR4 mutations (Asp299Gly and Thr399Ile) were associated with severe RSV bronchiolitis and were significantly over-represented in groups II and III. 16542364 2006
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
0.070 GeneticVariation BEFREE The association of the TLR4 mutations (Asp299Gly and Thr399Ile) and the CD14/-159 polymorphism were analyzed in 99 infants hospitalized with severe RSV bronchiolitis (group I). 15143473 2004