rs4986791, TLR4

N. diseases: 182
Disease: Tuberculosis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.050 GeneticVariation BEFREE In conclusion, our data suggest that TLR4 (D299G and T399I) and TNF (-308G/A) genetic polymorphisms may influence the risk of developing tuberculosis after exposure to Mycobacterium. 26774366 2016
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.050 GeneticVariation BEFREE The T allele of TLR4 rs4986791 was also found to increase the risk of TB in the Asian subgroup. 26430737 2015
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.050 GeneticVariation BEFREE The present meta-analysis suggests that TLR4 gene Asp299Gly and Thr399Ile polymorphisms are not associated with the susceptibility of tuberculosis. 23200920 2013
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.050 GeneticVariation BEFREE The association between two particular SNPs in human TLR4 (Asp299Gly and Thr399Ile) and active TB has been studied in non-HIV Africans with contradictory results. 20226000 2010
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.050 GeneticVariation BEFREE Polymorphisms of the toll-like receptor 2 (TLR2) gene (Arg677Trp, Arg753Gln) and the TLR4 gene (Asp299Gly, Thr399Ile) were investigated in 205 tuberculosis (TB) patients and 203 controls. 20002809 2010