rs4986791, TLR4

N. diseases: 182
Disease: Glaucoma, Primary Open Angle ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Glaucoma, Primary Open Angle
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
0.040 GeneticVariation BEFREE The minor alleles of rs4986791 and rs2149356 within TLR4 gene, interaction between rs2149356 and alcohol drinking were all associated with increased POAG risk. 31697008 2020
Glaucoma, Primary Open Angle
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
0.040 GeneticVariation BEFREE Moreover, rs4986790 A/G and rs4986791 C/T showed a stringent association with POAG in allele contrast, heterozygous, recessive, and overdominant models. 30877182 2019
Glaucoma, Primary Open Angle
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
0.040 GeneticVariation BEFREE TLR4 coding SNPs Asp299Gly and Thr399Ile might be used as genetic susceptibility alleles for POAG in Mexican population. 28214954 2017
Glaucoma, Primary Open Angle
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
0.040 GeneticVariation BEFREE We did not detect any direct association between genotypes or allele frequencies of SNP rs4986791 in the TLR4 gene and POAG. 27526043 2016