Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Irritable Bowel Syndrome
CUI: C0022104
Disease: Irritable Bowel Syndrome
0.040 GeneticVariation BEFREE In elderly Chinese patients, the 158Met SNP in COMT is associated with IBS pathogenesis, but the GNβ3-C825T SNP is not associated with IBS pathogenesis. 25037115 2014
Irritable Bowel Syndrome
CUI: C0022104
Disease: Irritable Bowel Syndrome
0.040 GeneticVariation BEFREE The present study suggests no associations of GNB3 C825T polymorphism with IBS risk. 24876757 2014
Irritable Bowel Syndrome
CUI: C0022104
Disease: Irritable Bowel Syndrome
0.040 GeneticVariation BEFREE We evaluated the association of the GNB3 C825T polymorphism with GERD and GERD subgroups classified according to esophageal acid exposure time, symptom-reflux correlation, or coexistence of FD and/or irritable bowel syndrome (IBS) symptoms. 19174793 2009
Irritable Bowel Syndrome
CUI: C0022104
Disease: Irritable Bowel Syndrome
0.040 GeneticVariation BEFREE Whereas no specific gene has been identified in association with IBS, recent studies have noticed the importance of polymorphisms in the promoter region of the serotonin reuptake transporter gene, G-protein beta 3 subunit gene (C825T), cholecystokinin receptor (CCKAR gene 779T>C), and high-producer tumor necrosis factor genotype. 19034965 2008