rs5443, CDCA3;GNB3

N. diseases: 106
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE Clinically silent adrenal adenomas - their relation to the metabolic syndrome and to GNB3 C825T gene polymorphism. 21979884 2011
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE The Gly972Arg and C825T polymorphisms are associated neither with PCOS nor with metabolic syndrome in the Slovak female population. 20170352 2010
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE A common 825C>T polymorphism in exon 10 of the gene for the beta-3 subunit of heterotrimeric G-proteins, GNB3, has been associated in some studies with traits of the metabolic syndrome as well as coronary artery disease (CAD), but these associations were refuted by other studies. 16908025 2007
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE The present study suggests no major involvement of the GNB3 825C>T polymorphism in components of the metabolic syndrome. 16284746 2006
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE AGT T174M, GNB3 825C>T, and APOC3 -455T>C genotypes were significantly associated with MetS (P = 0.018, 0.0056, and 0.029, respectively) for female adults, whereas FABP2 A54T genotype was associated with MetS (P = 0.040) for female adolescents. 15869758 2006
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE The C825T polymorphism in the gene coding for the beta3 subunit of G proteins (GNB3) has been shown to be associated with several phenotypes such as hypertension, obesity, and diabetes mellitus comprising the metabolic syndrome. 15033462 2004