rs5443, CDCA3;GNB3

N. diseases: 106
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.040 GeneticVariation BEFREE In the current study, 729 patients (CC, n = 332; CT, n = 313; TT, n = 84) with essential hypertension were genotyped for C825T polymorphism of the GNB3 gene and followed 8 years for major adverse cardiovascular events (MACEs) which include stroke, the onset of coronary artery disease (CAD), and all-cause death. 28067546 2017
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.040 GeneticVariation BEFREE To investigate the role of GNB3 gene variations in CAD and myocardial infarction (MI), we determined five GNB3 polymorphisms (-1429G>A, IVS5 +41G>A, 657T>A, 814G>A and 825C>T) in the Ludwigshafen Risk and Cardiovascular Health (LURIC) cohort, including 2575 patients with angiographically documented CAD and 731 individuals in whom CAD had been ruled out by angiography. 16908025 2007
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.040 GeneticVariation BEFREE We tested whether GNB3 C825T is associated with an increased risk of coronary artery disease (CAD). 12618278 2003
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.040 GeneticVariation BEFREE C825T polymorphism in the G protein beta3 subunit gene (GNB3) has been associated with arterial hypertension, coronary artery disease and myocardial infarction. 10704626 2000