rs5743618, TLR1

N. diseases: 25
Disease: Tuberculosis, Pulmonary ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Tuberculosis, Pulmonary
CUI: C0041327
Disease: Tuberculosis, Pulmonary
0.040 GeneticVariation BEFREE Our findings revealed that TLR1 rs5743551 and rs5743618 polymorphisms affected the risk of PTB in an Iranian population sample. 27998389 2016
Tuberculosis, Pulmonary
CUI: C0041327
Disease: Tuberculosis, Pulmonary
0.040 GeneticVariation BEFREE T1805G, a functional TLR1 single nucleotide polymorphism (SNP), has been associated with susceptibility to pulmonary tuberculosis (PTB), but contradictory results among different populations have been reported. 23575331 2013
Tuberculosis, Pulmonary
CUI: C0041327
Disease: Tuberculosis, Pulmonary
0.040 GeneticVariation BEFREE The aim of this study was to investigate whether the functional genetic variations at position 1805 G/T in TLR1, 2258 A/G in TLR2, -857 C/T, and -863 A/C in tumor necrosis factor-α (TNF-α), as well as -819 C/T in interleukin-10 (IL-10) confer susceptibility to pulmonary tuberculosis (PTB). 20650298 2010
Tuberculosis, Pulmonary
CUI: C0041327
Disease: Tuberculosis, Pulmonary
0.040 GeneticVariation BEFREE In the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G/A (Arg753Gln), TLR-4 896A/G (Asp299Gly), TLR-4 1196C/T (Thr399Ile), TLR-6 745C/T (Ser249Pro), TIRAP 975C/T (Ser180Leu) genes and TLR-9 promoter region polymorphisms at positions -1237C/T and -1486C/T are associated with susceptibility or resistance to pulmonary tuberculosis (PTB). 20797905 2010