rs5743618, TLR1

N. diseases: 25
Disease: Lower respiratory tract infection ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Lower respiratory tract infection
CUI: C0149725
Disease: Lower respiratory tract infection
0.010 GeneticVariation BEFREE Our findings reveal that single-nucleotide polymorphisms within toll-interleukin 1 receptor domain-containing adaptor protein (<i>TIRAP</i>) alone or in combination with TLR1 N248S, TLR1 I602S, or TLR6 S249P polymorphisms contributes to various degree of susceptibility to recurrent pneumococcal LRTI in children by modulating the inflammatory response. 30131804 2018