|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
It is suggested that MIF participates in the amplification of the proinflammatory process in SSc; moreover, the promoter polymorphisms - 794 CATT<sub>5-8</sub> (rs5844572) and - 173G>C (rs755622) in the MIF gene have been associated with an increase in MIF serum levels in several autoimmune diseases.
|
30747392 |
2019 |
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
Two polymorphisms, rs755622 and rs5844572, in the promoter region of the macrophage migration inhibitory factor (MIF) gene influence the basal and/or induced transcriptional activity and have been linked to several inflammatory and autoimmune diseases.
|
28657145 |
2017 |
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to evaluate the association of MIF promoter polymorphisms (-794CATT<sub>5-8</sub> rs5844572 and -173G > C, rs755622), circulating MIF levels, and mRNA expression with RA susceptibility and disease activity.
|
31701681 |
2020 |
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation
|
BEFREE |
It is suggested that MIF participates in the amplification of the proinflammatory process in SSc; moreover, the promoter polymorphisms - 794 CATT<sub>5-8</sub> (rs5844572) and - 173G>C (rs755622) in the MIF gene have been associated with an increase in MIF serum levels in several autoimmune diseases.
|
30747392 |
2019 |
|
Granulomatosis with polyangiitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The human study involved 1,077 patients with GPA and healthy controls whose serum was genotyped by capillary electrophoresis for the MIF -794 CATT<sub>5-8</sub> promoter microsatellite (rs5844572).
|
29953750 |
2018 |
|
Multiple Sclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Therefore, we decided to investigate the genetic association of -794 CATT<sub>5-8</sub> (rs5844572) and -173 G>C (rs755622) MIF polymorphisms with MS, clinical variables and MIF serum levels in the population of western Mexico.
|
29661540 |
2018 |
|
Congenital atresia of extrahepatic bile duct
|
|
0.010 |
GeneticVariation
|
BEFREE |
The homozygous and heterozygous short repeats (5/5, or 5/X) of rs5844572</span> were observed more frequently (16/28, 57.1%) in BA patients with mild to moderate fibrosis compared with those with marked fibrosis (10/32, 31.3%).
|
28657145 |
2017 |
|
Biliary Atresia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The homozygous and heterozygous short repeats (5/5, or 5/X) of rs5844572</span> were observed more frequently (16/28, 57.1%) in BA patients with mild to moderate fibrosis compared with those with marked fibrosis (10/32, 31.3%).
|
28657145 |
2017 |
|
Meningitis, Pneumococcal
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two functional MIF promoter polymorphisms, a microsatellite (-794 CATT5-8; rs5844572) and a single-nucleotide polymorphism (-173 G/C; rs755622) were genotyped in a prospective, nationwide cohort of 405 patients with pneumococcal meningitis and in 329 controls matched for age, gender, and ethnicity.
|
26976591 |
2016 |
|
Autoimmune hepatitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two MIF promoter polymorphisms, a functional -794 CATT5-8 microsatellite repeat (rs5844572) and a -173 G/C single-nucleotide polymorphism (rs755622), were analyzed in DNA samples from over 500 patients with AIH, PBC, and controls.
|
23913513 |
2014 |
|
Autoimmune Chronic Hepatitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two MIF promoter polymorphisms, a functional -794 CATT5-8 microsatellite repeat (rs5844572) and a -173 G/C single-nucleotide polymorphism (rs755622), were analyzed in DNA samples from over 500 patients with AIH, PBC, and controls.
|
23913513 |
2014 |
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two functional polymorphisms in the MIF gene, a -794 CATT(5-8) microsatellite repeat (rs5844572) and a -173 G/C single-nucleotide polymorphism (rs755622), were assessed for association with SLE in 3,195 patients and healthy controls.
|
22127710 |
2011 |