|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
MSH2 missense mutations and HNPCC syndrome: pathogenicity assessment in a human expression system.
|
18781619 |
2008 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Influence of selection criteria on mutation detection in patients with hereditary nonpolyposis colorectal cancer.
|
10375096 |
1999 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
A large fraction of unclassified variants of the mismatch repair genes MLH1 and MSH2 is associated with splicing defects.
|
18561205 |
2008 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Identification of individuals at risk for Lynch syndrome using targeted evaluations and genetic testing: National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer joint practice guideline.
|
22167527 |
2012 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Population-based molecular detection of hereditary nonpolyposis colorectal cancer.
|
10829038 |
2000 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.
|
27854360 |
2017 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.
|
23788249 |
2013 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Hereditary nonpolyposis colorectal cancer: pitfalls in deletion screening in MSH2 and MLH1 genes.
|
15870828 |
2005 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical Practice Guideline endorsement of the familial risk-colorectal cancer: European Society for Medical Oncology Clinical Practice Guidelines.
|
25452455 |
2015 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer.
|
25003300 |
2014 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing.
|
25356965 |
2015 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 in Japanese hereditary nonpolyposis colorectal cancer kindreds.
|
9419403 |
1997 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
|
9718327 |
1998 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.
|
12658575 |
2003 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Informing family members of individuals with Lynch syndrome: a guideline for clinical geneticists.
|
23535968 |
2013 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
American Society of Clinical Oncology policy statement update: genetic and genomic testing for cancer susceptibility.
|
20065170 |
2010 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-society Task Force on colorectal cancer.
|
25070057 |
2014 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment.
|
25394175 |
2015 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Practice parameters for the identification and testing of patients at risk for dominantly inherited colorectal cancer--supporting documentation.
|
11598466 |
2001 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Functional analysis of human MutSalpha and MutSbeta complexes in yeast.
|
9889267 |
1999 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers.
|
24493721 |
2014 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes.
|
25645574 |
2015 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Four novel MSH2 / MLH1 gene mutations in portuguese HNPCC families.
|
10612836 |
2000 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Assessment of pathogenicity criteria for constitutional missense mutations of the hereditary nonpolyposis colorectal cancer genes MLH1 and MSH2.
|
10573010 |
2000 |
|
Colorectal cancer, hereditary nonpolyposis, type 1
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Verification of the three-step model in assessing the pathogenicity of mismatch repair gene variants.
|
21120944 |
2011 |