DisGeNET - a database of gene-disease associations

rs5918, ITGB3

N. diseases: 26

Disease: Carcinoma, Ovarian Epithelial ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Carcinoma, Ovarian Epithelial

CUI:	C4721610
Disease:	Carcinoma, Ovarian Epithelial

0.030

GeneticVariation

BEFREE

The ITGB3 Leu33Pro polymorphism does not modify breast or ovarian cancer risk in BRCA1 or BRCA2 mutation carriers.

19876733

2010

Carcinoma, Ovarian Epithelial

CUI:	C4721610
Disease:	Carcinoma, Ovarian Epithelial

0.030

GeneticVariation

BEFREE

Integrin beta3 Leu33Pro polymorphism increases BRCA1-associated ovarian cancer risk.

17220212

2007

Carcinoma, Ovarian Epithelial

CUI:	C4721610
Disease:	Carcinoma, Ovarian Epithelial

0.030

GeneticVariation

BEFREE

Integrin beta(3) Leu33Pro homozygotes have an increased risk of ovarian cancer.

16322334

2005