rs61754966, NBN

N. diseases: 23
Disease: Malignant neoplasm of larynx ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of larynx
CUI: C0007107
Disease: Malignant neoplasm of larynx
0.030 GeneticVariation BEFREE We have previously shown that the p.I171V NBN gene mutation may contribute to the development of laryngeal cancer. 24079363 2013
Malignant neoplasm of larynx
CUI: C0007107
Disease: Malignant neoplasm of larynx
0.030 GeneticVariation BEFREE Positive associations have also been reported for leukaemia and larynx cancer suggesting that I171V could be a more general susceptibility factor for malignancies. 18049891 2008
Malignant neoplasm of larynx
CUI: C0007107
Disease: Malignant neoplasm of larynx
0.030 GeneticVariation BEFREE These findings imply that heterozygous carriers of the I171V mutation are prone to the development of larynx cancer and may, in addition, display an increased risk of second tumors at other sites. 17894553 2007