|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association Between the Brain-derived Neurotrophic Factor Val66Met Polymorphism and Overweight/Obesity in Pediatric Population.
|
29506764 |
2017 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
A common polymorphism of the BDNF genotype (Val66Met) has been associated with various forms of eating disorders, alterations in body mass index (BMI) values and obesity in adult populations.
|
21851847 |
2012 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
BDNF196G/G genotype was more common and BDNF 196G/A polymorphism was less common among OSAS+ obesity- subjects compared to the other study groups.
|
27166632 |
2016 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
No association was found between the BDNF G196A (Val66Met) polymorphism and diabetes or obesity.
|
17151862 |
2007 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Variants in BDNF, in particular the functional Val66Met polymorphism (rs6265), have been found to be associated with a number of psychiatric disorders, cognitive function, and obesity.
|
24708359 |
2015 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
In addition, BDNF rs6265 and MC4R rs17782313 showed gender-dependent associations with decreased risk of having low HDL-C in males and increased risk of having abdominal obesity in females, respectively.
|
31502573 |
2019 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The positive association of BNDF Val66Met with high BMI values replicates previous findings in patients with SCZ and indicates the BDNF Val66Met genotype as a potential risk factor for obesity and insulin resistance measures in patients with BPD receiving antipsychotics as well.
|
25874530 |
2015 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Most notably, the association between 5 SNPs (Fas apoptotic inhibitory molecule 2 rs7138803, Niemann-Pick disease, type C1 rs1805081, fat mass- and obesity-associated gene rs6499640, melanocortin 4 receptor gene rs17782313, and brain-derived neurotrophic factor rs6265) and obesity risk was only observed in children who had moderate-to-low physical activity levels or engaged in sedentary behavior, regardless of which risk alleles they carried.
|
21527513 |
2011 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The SNP rs6265 was significantly associated with adiponectin under an additive model (<i>P</i> = 0.02 and 0.024, resp.) after adjustment for age, gender, and BMI or obesity statuses.
|
28396685 |
2017 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association of the BDNF Val66Met variation with obesity in women.
|
18667348 |
2008 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The BDNF rs6265, in the presence of obesity, may be associated with elevated risk of anomalous metabolic, behavioural and physical traits and obesity-related co-morbidities, but it needs to be validated in a significantly larger Pakistani sample population.
|
30590963 |
2019 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
After age and sex adjustment and correction for multiple testing, the SNPs rs17782313, rs6265, and rs10938397 were associated with BMI (P = 1.0 × 10⁻⁵, 0.038, and 0.00093, respectively) and also obesity (P = 5.0 × 10⁻⁶, 0.043, and 0.00085, respectively) in the Chinese children.
|
20843981 |
2010 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The amino acid-changing exonic variant rs6265 (Val66Met polymorphism) in the brain-derived neurotrophic factor (BDNF) has been linked to obesity in several genotype-phenotype association studies.
|
28960774 |
2018 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
The study suggested the significant association of delivery method, birth weight, night sleep duration, and BDNF Val66Met polymorphism, with obesity in Vietnamese primary school children.
|
28471701 |
2017 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our study replicates the statistically significant association of four SNPs (FTO rs9939609, MC4R rs17782313, GNPDA2 rs10938397, BDNF rs6265) with risk of central obesity in the Chinese children.
|
23424664 |
2013 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our aim is to elucidate whether the interaction between the Brain Derived Neurotrophic Factor val66met polymorphism and obesity status influences executive performance and frontal-subcortical brain structure.
|
24619555 |
2014 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
BDNF rs6265 polymorphism is associated with BMI categories, and the BDNF Met/Met genotype has a protective role in obesity in healthy subjects, while this effect was not present in patients with CHD.
|
27608901 |
2016 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
In a partial replication of prior research, the obesity risk (G) allele at BDNF rs6265 was associated with greater weight regain across treatment arms (0.773 kg per risk allele), although results were of borderline statistical significance (P=0.051).
|
23628854 |
2013 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
We found no association between p.V66M or the additionally genotyped variant c.-46C > T and obesity, ADHD or eating disorders.
|
15457498 |
2005 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this cross-sectional study, the rs6265 polymorphism was not associated with a higher risk of obesity, or lower circulating levels of BDNF.
|
30418087 |
2019 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
It seems that plasma BDNF levels were associated with both ob</span>esity and BDNF V</span>al66Met SNP.
|
31004714 |
2019 |