rs6265, BDNF;BDNF-AS

N. diseases: 272
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Anorexia Nervosa
CUI: C0003125
Disease: Anorexia Nervosa
0.080 GeneticVariation BEFREE Higher reward value of starvation imagery in anorexia nervosa and association with the Val66Met BDNF polymorphism. 27271855 2016
Anorexia Nervosa
CUI: C0003125
Disease: Anorexia Nervosa
0.080 GeneticVariation BEFREE Our analyses indicate that the BDNF Val66Met variant is not associated with AN at detectable levels. 21936709 2013
Anorexia Nervosa
CUI: C0003125
Disease: Anorexia Nervosa
0.080 GeneticVariation BEFREE No difference was found in minimum BMIs related to Val66Met in AN (one-way ANOVA, P > 0.05). 22127997 2012
Anorexia Nervosa
CUI: C0003125
Disease: Anorexia Nervosa
0.080 GeneticVariation BEFREE BDNF has been involved in body weight regulation and its Val66Met polymorphism associated with AN. 17197106 2007
Anorexia Nervosa
CUI: C0003125
Disease: Anorexia Nervosa
0.080 GeneticVariation BEFREE Some studies have shown association of BDNF -270C/T single-nucleotide polymorphism (SNP) with bulimia nervosa (BN), while BDNF Val66Met variant has been shown to be associated with both BN and anorexia nervosa (AN). 17376155 2007
Anorexia Nervosa
CUI: C0003125
Disease: Anorexia Nervosa
0.080 GeneticVariation BEFREE Case-control studies also suggest a BDNF contribution in the aetiology of ED: we have previously reported a strong association between the Met66 variant within the BDNF gene, restricting AN (ANR) and minimum body mass index (minBMI) in a Spanish sample, and a positive association between the Val66Met and -270C/T BDNF SNPs and ED in six different European populations. 15657604 2005
Anorexia Nervosa
CUI: C0003125
Disease: Anorexia Nervosa
0.080 GeneticVariation BEFREE Additionally, we genotyped two common polymorphisms (rs6265: p.V66M; c.-46C > T) in 118 patients with anorexia nervosa, 80 patients with bulimia nervosa, 88 patients with ADHD, and 96 normal weight controls. 15457498 2005
Anorexia Nervosa
CUI: C0003125
Disease: Anorexia Nervosa
0.080 GeneticVariation BEFREE We previously reported a strong association of the Met66 allele of the Val66Met BDNF variant with restricting AN (ANR) and low minimum body mass index in Spanish patients. 15115760 2004