|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Brain-Derived Neurotrophic Factor Val66Met Polymorphism Affects the Relationship Between an Anxiety-Related Personality Trait and Resting Regional Cerebral Blood Flow.
|
27005989 |
2017 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism influences the association of the methylome with maternal anxiety and neonatal brain volumes.
|
25640836 |
2016 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
On the contrary, BDNF met allele carriers showed a reduced acoustic startle response which reached significance in most samples (N1: p=0.004; N2: p=0.045; N3: n.s., N4: p=0.043) pointing to differential effects of BDNF val(66)met on distinct endophenotypes of anxiety and stress-related responses.
|
26773399 |
2016 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Here we comprehensively review the role and relevance of the Val66Met polymorphism in psychiatric disorders, with emphasis on suicidal behavior and anxiety, eating, mood and psychotic disorders.
|
25824305 |
2016 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
We investigated the effect of brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism on the severity of depressive and anxiety symptoms in never-smokers, former smokers, non-dependent, and nicotine-dependent smokers with a current diagnosis of depression and/or anxiety.
|
25618300 |
2015 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Gene-environment interaction effects were detected between the BDNF-Val66Met polymorphism and maternal care on phobic anxiety, paternal care on hostility, maternal overprotection on somatization and paternal overprotection also in somatization.
|
24768157 |
2015 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
The Val/Val genotype of the brain-derived neurotrophic factor (BDNF) polymorphism (Val66Met) has been reported to affect human anxiety-related phenotypes.
|
25001952 |
2015 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
We aimed to explore whether anxiety in BD offspring was associated with the BDNF Val66Met polymorphism.64 BD offspring (mean age: 13.73 (S.D.
|
25498133 |
2015 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
The Met allele of BDNF Val66Met may be predictive of an anxious coping style in patients with advanced cancer.
|
24913346 |
2014 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Because the Val/Val genotype of the BDNF Val66Met polymorphism, rather than the other two polymorphisms, has been associated with anxiety, it seems to affect BP-I comorbid with AD without the involvement of the DRD3 Seg9Gly polymorphism, but may modify the involvement of DRD3 Gly/Gly in BP-II comorbid with AD.
|
24021960 |
2014 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Gray matter volume in adolescent anxiety: an impact of the brain-derived neurotrophic factor Val(66)Met polymorphism?
|
23357445 |
2013 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
BDNF Val66Met polymorphism is associated with higher anticipatory cortisol stress response, anxiety, and alcohol consumption in healthy adults.
|
21596481 |
2012 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
BDNF gene polymorphism (Val66Met) predicts amygdala and anterior hippocampus responses to emotional faces in anxious and depressed adolescents.
|
19931400 |
2011 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
In line with recent studies investigating the role of BDNF Val66Met and DRD2/ANKK1 Taq IA polymorphisms on anxiety and gray matter volume in the ACC, our findings provide the first evidence for a genetic contribution to alexithymia.
|
21097659 |
2011 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
A common polymorphism of the brain-derived neurotrophic factor (BDNF) gene (Val66Met) has been implicated in anxiety, which is associated with lower vagal activity.
|
20213725 |
2010 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Association of COMT (Val158Met) and BDNF (Val66Met) gene polymorphisms with anxiety, ADHD and tics in children with autism spectrum disorder.
|
19582565 |
2010 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety.
|
19153574 |
2009 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits.
|
17392738 |
2008 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Two common functional polymorphisms in catechol-O-methyltransferase (COMT Val158Met) and brain-derived neurotrophic factor (BDNF Val66Met) genes have been implicated in the neurobiology of anxiety and depression.
|
17941097 |
2008 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Moreover, the Val66Met polymorphism was correlated with improvements in core, activity, and psychic anxiety symptoms.
|
16979146 |
2007 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
Assuming that BDNF may be implicated in the putative common pathophysiology of depression and anxiety, we analyzed the association of two BDNF gene single nucleotide polymorphisms (SNPs), 132C > T (formerly named C270T) in the noncoding region of exon V and 196G > A (val66met) in the coding region of exon XIIIA, with panic disorder.
|
15913870 |
2005 |
|
Anxiety
|
0.100 |
GeneticVariation
|
BEFREE |
BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects.
|
15770238 |
2005 |