Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The effects of age on val66met associated alteration</span>s in plasticity and potential </span>consequences in terms of stroke are also discussed. 30118755 2019
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The BDNF Val66Met polymorphism was not independently associated with PSA during either the acute or chronic phase after stroke, but there was a significant interactive effect between BDNF methylation and genotype on PSA at 2 weeks. 31368178 2019
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE Conclusions Our results suggest that the Val66Met polymorphism does not predict long-term, functional mobility following stroke. 29480080 2018
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE BDNF Val66Met is a determinant of motor skill learning after stroke and could be important for prognostic models. tDCS does not modulate motor skill learning in our study and might be less effective than previously assumed. 28751226 2018
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE Sixteen dysphagic stroke patients that completed a single-blind randomized sham controlled trial of pharyngeal electrical stimulation (PES) within 6 weeks of their stroke (N=38), were genotyped for the BDNF SNP Val66Met (rs6265) from saliva samples. 28317287 2017
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The Role of the BDNF Val66Met Polymorphism in Recovery of Aphasia After Stroke. 28818006 2017
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The current study examined whether the presence of the BDNF val(66)met polymorphism is associated with reduced motor system activation after stroke. 26381810 2016
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with functional and cognitive outcomes of stroke and plays a key role in preventing neuronal death. 27071687 2016
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The impact of the Val66Met polymorphism on motor learning post-stroke has not been explored. 26487176 2016
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The brain-derived neurotrophic factor Val66Met polymorphism and degeneration of the corticospinal tract after stroke: a diffusion tensor imaging study. 26228236 2016
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE For the first time in an Iranian population, it was demonstrated that BDNF G196A variant plays a major role in stroke occurrence and consequences. 27077983 2016
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE To investigate the impact of this common BDNF SNP on stroke recovery, we used a mouse model that contains the human BDNF Val66Met variant in both alleles (BDNF(M/M)). 24523540 2014
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The aim of present study was to assess the role of BDNF -196 G≯A (val66met) and -270 C≯T on clinical parameters and functional outcome in patients with ischemic and hemorrhagic stroke. 24722042 2014
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE This study aimed to investigate whether BDNF gene promoter methylation status and val66met polymorphism were associated with depression ascertained at two weeks and one year after stroke. 23399480 2013
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The AA genotype of the BDNF G196A was associated with a poor outcome of recovery 3 months after stroke onset (P=0.008) was a novel finding, independent of other known predictors of poor outcome (P=0.012). 24035862 2013
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE This study hypothesized that the ApoE ε4 polymorphism and the val(66) met polymorphism for brain-derived neurotrophic factor (BDNF) are each associated with poorer outcome after stroke. 22221491 2012
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE This study aimed to investigate whether BDNF val66met polymorphism and promoter methylation status were associated with outcomes at two weeks and one year after stroke. 23240009 2012
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE Genetic variant of BDNF (Val66Met) polymorphism attenuates stroke-induced angiogenic responses by enhancing anti-angiogenic mediator CD36 expression. 21228186 2011
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.100 GeneticVariation BEFREE The BDNF val66met polymorphism may modify the association between stroke and depression. 17222482 2008