Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Major Depressive Disorder
CUI: C1269683
Disease: Major Depressive Disorder
0.020 GeneticVariation BEFREE The rs6296-C allele lowered the level of HTR1B mRNA, causing individuals with MDD to display more hostility and aggressive behavior, which may lead to suicidal ideation. 28007644 2017
Major Depressive Disorder
CUI: C1269683
Disease: Major Depressive Disorder
0.020 GeneticVariation BEFREE Substance abuse disorder and major depression are associated with the human 5-HT1B receptor gene (HTR1B) G861C polymorphism. 12496953 2003