rs63749835, PSEN1

N. diseases: 5
Disease: Personality Change ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Personality Change
CUI: C0240735
Disease: Personality Change
0.010 GeneticVariation BEFREE In the present study, a novel mutation in exon 7 of presenilin 1 (Leu232Pro) was discovered in a Korean patient with early-onset Alzheimer's disease, who represented memory decline at 37 years of age, followed by impairment in spatial activity and concentrations and personality changes. 28532645 2017