rs642961, None

N. diseases: 14
Disease: Cleft lip or lips ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cleft lip or lips
CUI: C4321245
Disease: Cleft lip or lips
0.030 GeneticVariation BEFREE We observed association between rs642961 and cleft lip only (CLO) (P=0.009; odds ratio (OR) for AA genotype=1.83 [95% Confidence interval (CI), 0.64-5.31]; OR for AG genotype=1.72 [95% CI, 1.03-2.84]). 22887868 2012
Cleft lip or lips
CUI: C4321245
Disease: Cleft lip or lips
0.030 GeneticVariation BEFREE Lack of association between IRF6 polymorphisms (rs2235371 and rs642961) and non-syndromic cleft lip and/or palate in a Brazilian population. 19780991 2010
Cleft lip or lips
CUI: C4321245
Disease: Cleft lip or lips
0.030 GeneticVariation BEFREE In the single locus analyses, we found rs642961 AG and AG/AA genotypes were associated with increased risk of NSOC, especially cleft lip with or without cleft palate (CL/P) and cleft lip with cleft palate (CLP), while significantly decreased risks were associated with rs2235371 CT and CT/TT genotypes. 20799332 2010