rs6454674, CNR1

N. diseases: 5
Disease: Cocaine Dependence ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cocaine Dependence
CUI: C0600427
Disease: Cocaine Dependence
0.020 GeneticVariation BEFREE This study confirms the association between rs6454674 and CD. 21790903 2013
Cocaine Dependence
CUI: C0600427
Disease: Cocaine Dependence
0.020 GeneticVariation BEFREE The interaction between two independent CNR1 variants, ie, the G allele-containing genotypes of rs6454674 (SNP3(G+)), and the T/T genotype of rs806368 (SNP8(T)/T), significantly increased risk for CD in the EA family (P(GEE)=0.015) and EA case-control (P(regression)=0.003) samples. 19052543 2009