Coronary heart disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
In UK non CHD, UK CHD, Pakistani non CHD and Pakistani CHD respectively, for rs646776, per risk allele increase in LDL-C(mmol/l) was 0.18(0.04), 0.06(0.11), 0.15(0.04) and 0.27(0.06) respectively.
|
27112212 |
2016 |
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
No significant associations were observed between the other two SNPs in loci 1p13 (rs599839 and rs646776) and CHD mortality in either gender.
|
24728607 |
2014 |
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
Five single-nucleotide polymorphisms, rs4977574 (CDKN2A/2B), rs12526453 (PHACTR1), rs646776 (CELSR2-PSRC1-SORT1), rs2259816 (HNF1A), and rs11206510 (PCSK9) showed directionally consistent associations with CHD in the 3 studies, with combined odds ratios (ORs) ranging from 1.17 to 1.25 (p = 0.03 to 0.0002).
|
22152955 |
2011 |
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.
|
21239051 |
2011 |
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
|
21378988 |
2011 |
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
|
21378988 |
2011 |
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric analysis identifies novel variants for coronary artery disease.
|
21966275 |
2011 |
Coronary heart disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
Myocardial Infarction
|
|
0.810 |
GeneticVariation
|
BEFREE |
Three SNPs 12740374 G/T, rs599839A/G and rs646776T/C mapping at 1p13 were analysed for association with serum lipid levels and the risk of MI by a weighted least square regression and logistic regression analyses, respectively.
|
23067240 |
2012 |
Myocardial Infarction
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
19198609 |
2009 |
Myocardial Infarction
|
|
0.810 |
GeneticVariation
|
GWASDB |
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
|
19198609 |
2009 |
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of blood lipids in Indians confirms universality of established variants.
|
30911093 |
2019 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
|
30926973 |
2019 |
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
|
30926973 |
2019 |
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of blood lipids in Indians confirms universality of established variants.
|
30911093 |
2019 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
|
27286809 |
2016 |
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.
|
27286809 |
2016 |
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
The impact of low-frequency and rare variants on lipid levels.
|
25961943 |
2015 |
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
The impact of low-frequency and rare variants on lipid levels.
|
25961943 |
2015 |