rs671, ALDH2

N. diseases: 116
Disease: Hypertensive disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.060 GeneticVariation BEFREE Aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism is an established genetic risk of hypertension, diabetes, and coronary heart diseases in Asian population. 30846829 2020
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.060 GeneticVariation BEFREE The <i>ALDH2</i> rs671 genotypes indicated that the gene-related drinking habit and gene variant altogether may affect hypertension and dyslipidemia. 31361523 2019
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.060 GeneticVariation BEFREE In conclusion, this study supports a causal effect of alcohol intake on hypertension and indicated that alcohol flushing may be a valid proxy for the ALDH2 rs671 polymorphism, which influences alcohol intake in this Korean population. 29323248 2018
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.060 GeneticVariation BEFREE Our study suggested that ALDH2 rs671 L-genotypes are protective factors for hypertension in Han Chinese. 28894224 2017
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.060 GeneticVariation BEFREE ALDH2 rs671 polymorphism is proven to be closely related to the prevalence of CAD, hypertension, diabetes mellitus and alcoholism, which are etiological factors of heart failure. 27742538 2017
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.060 GeneticVariation BEFREE Furthermore, the ALDH2 Glu504Lys polymorphism has been shown to be associated with certain traditional cardiovascular risk factors, such as dyslipidemia, hypertension, and diabetes mellitus or hyperglycemia. 25263942 2014