rs671, ALDH2

N. diseases: 116
Disease: Essential Hypertension ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.070 GeneticVariation BEFREE We found no association between ALDH2 rs671 and EH risk or EH-related quantitative blood chemistry values. 28613083 2017
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.070 GeneticVariation BEFREE In addition, the results of the breakdown analysis by gender suggest a male-specific association between the ALDH2 rs671</span> polymorphism and EH. 28472173 2017
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.070 GeneticVariation BEFREE The Glu504Lys polymorphism of the ALDH2 gene is associated with the CIMT of Chinese Han patients with EH in Sichuan, China. 27270535 2016
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.070 GeneticVariation BEFREE The ALDH2 Glu504Lys polymorphism was associated with EDD disorders in Chinese Han patients with EH, providing further evidence that this mutation and 'alcohol flush' are not harmless in this Asian population. 26691593 2016
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.070 GeneticVariation BEFREE Further functional research is warranted to elucidate the role of rs671 in the variation of BP and lipid levels in EH. 22551939 2013
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.070 GeneticVariation BEFREE Acetaldehyde dehydrogenase 2 SNP rs671 and susceptibility to essential hypertension in Mongolians: a case control study. 21476199 2011
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.070 GeneticVariation BEFREE Case-control association analysis showed a significant association between EH and both the ALDH2 (Lys487Glu) and GNB3 (C825T) variants. 17785925 2007