rs67376798, DPYD

N. diseases: 9
Disease: Diarrhea ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Diarrhea
CUI: C0011991
Disease: Diarrhea
0.020 GeneticVariation BEFREE DPYD T85C, T1896C and A2846T mutant variants were associated with diarrhea (P < 0.05) and HFS (P < 0.02), and IVS14+1G>A additionally with diarrhea (P < 0.001). 25677447 2015
Diarrhea
CUI: C0011991
Disease: Diarrhea
0.020 GeneticVariation BEFREE The DPYD*2A variant statistically significantly associated with the specific AEs nausea/vomiting (P = .007) and neutropenia (P < .001), whereas D949V statistically significantly associated with dehydration (P = .02), diarrhea (P = .003), leukopenia (P = .002), neutropenia (P < .001), and thrombocytopenia (P < .001). 25381393 2014