rs6749447, STK39

N. diseases: 2
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Blood Pressure
CUI: C0005823
Disease: Blood Pressure
0.800 GeneticVariation GWASDB From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. 19114657 2009
Blood Pressure
CUI: C0005823
Disease: Blood Pressure
0.800 GeneticVariation GWASCAT From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene. 19114657 2009
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE However, the TT genotype ratio in rs6749447</span> was lower in hypertensives (5.4% vs 10.8%, P < 0.05), and the hypertension</span> risk for the TT genotype carriers in rs6749447 decreased after adjustment (OR 0.49, 95% CI 0.19-0.95, P < 0.05). 28945285 2018
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE Overall analyses failed to see any significant associations of rs6749447, rs35929607 and rs3754777 with hypertension risk (odds ratio: 1.27, 0.95 and 1.21; P = 0.270, 0.507 and 0.153, respectively), and there was evident heterogeneity for three comparisons (I(2) > 80%). 27142475 2016
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.030 GeneticVariation BEFREE In conclusion, there was a significant association between STK39 genetic variant rs6749447 and hypertension in a Finnish cohort. 23235358 2013