rs689, INS;INS-IGF2

N. diseases: 9
Disease: Latent autoimmune diabetes mellitus in adult ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Latent autoimmune diabetes mellitus in adult
CUI: C1960272
Disease: Latent autoimmune diabetes mellitus in adult
0.020 GeneticVariation BEFREE The rs2476601C/T, rs689A/T, and rs7903146C/T polymorphisms were found to be associated with the risk of LADA, thereby indicating that, genetically, LADA could be an admixture of both T1D and T2D. 30456822 2019
Latent autoimmune diabetes mellitus in adult
CUI: C1960272
Disease: Latent autoimmune diabetes mellitus in adult
0.020 GeneticVariation BEFREE The AA genotype of rs689, referring to the class I allele in the INS VNTR, as well as the CT/TT genotypes of rs2476601 in the PTPN22 gene, were increased both in type 1 diabetic (P = 3 x 10(-14) and P = 1 x 10(-10), respectively) and LADA (P = 0.001 and P = 0.002) subjects compared with control subjects. 18310307 2008