rs6897932, IL7R

N. diseases: 25
Disease: HIV Infections ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
HIV Infections
CUI: C0019693
Disease: HIV Infections
0.020 GeneticVariation BEFREE In conclusion, increased signal transduction and proliferation in response to IL-7 was found in 'TT' compared to 'CC' HIV-infected individuals providing a mechanistic explanation of the effect of rs6897932 T-allele on CD4+ T cell recovery in HIV infection. 28181541 2017
HIV Infections
CUI: C0019693
Disease: HIV Infections
0.020 GeneticVariation BEFREE The T-allele in the single nucleotide polymorphism rs6897932 in the gene encoding the IL-7 receptor α (IL7RA) is associated with reduced risk of autoimmune diseases including multiple sclerosis and also affects the course of HIV infection. 25421942 2015