rs6903608, HLA-DRB9

N. diseases: 11
Disease: Purpura, Thrombotic Thrombocytopenic ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Purpura, Thrombotic Thrombocytopenic
CUI: C0034155
Disease: Purpura, Thrombotic Thrombocytopenic
0.010 GeneticVariation BEFREE Results and conclusion We identified one common variant (rs6903608) located within the HLA class II locus that was independently associated with acquired TTP at genome-wide significance and conferred a 2.6-fold increased risk of developing a TTP episode (95% confidence interval [CI] 2.02-3.27, P = 1.64 × 10<sup>-14</sup> ). 27762046 2016