Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer. 30529582 2019
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Novel Common Genetic Susceptibility Loci for Colorectal Cancer. 29917119 2019
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. 30104761 2018
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. 29471430 2018
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci. 28960316 2018
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk. 26965516 2016
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Genome-wide association study of colorectal cancer identifies six new susceptibility loci. 26151821 2015
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. 24836286 2014
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation BEFREE A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 families enrolled in the Colon Cancer Family Registry, were genotyped for the single nucleotide polymorphisms (SNPs): rs16892766 (8q23.3), rs6983267 (8q24.21), rs719725 (9p24), rs10795668 (10p14), rs3802842 (11q23.1), rs4444235 (14q22.2), rs4779584 (15q13.3), rs9929218 (16q22.1), rs4939827 (18q21.1), rs10411210 (19q13.1) and rs961253 (20p12.3). 23434150 2013
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. 23266556 2013
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation BEFREE Rectal tumors were significantly associated with rs4939827 (OR = 4.85, P = 0.002) and rs6983267 (OR = 3.00, P = 0.036), suggesting that carriers of risk alleles at these loci had increased susceptibility to development of rectal cancer rather than colon cancer. 22457859 2012
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation BEFREE The two SNPs did not influence the development of distant metastases of colon cancer; rs6983267 showed a mild effect on breast cancer. 22666420 2012
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT Common variant in 6q26-q27 is associated with distal colon cancer in an Asian population. 21242260 2011
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation BEFREE This result replicates previous reports of association between rs6983267 and prostate and colon cancer. 22142333 2011
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation BEFREE The combined results for our two studies of colon cancer showed an OR of 1.10 (95% CI: 1.01-1.20, Ptrend = 0.023), and a meta-analysis of our results with previously reported studies of colon and colorectal cancer strongly support the association for this SNP (combined OR for rs6983267 = 1.21, 95% CI: 1.18-1.24, p = 5.5 × 10-44). 21129217 2010
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation BEFREE We observed significant associations with colon cancer risk with markers rs13254738 (ordinal odds ratio, 0.82; 95% confidence interval, 0.072-0.94; P(trend) = 0.0037) and rs6983267 (ordinal odds ratio, 1.17; 95% confidence interval, 1.03-1.32, P(trend) = 0.013). 19690179 2009
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation BEFREE These data replicate the association identified from recent studies, providing additional evidence supporting the rs6983267 genetic polymorphism as a marker predisposing to colon cancer. 18268117 2008
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. 18372905 2008
Malignant tumor of colon
CUI: C0007102
Disease: Malignant tumor of colon
0.770 GeneticVariation GWASCAT A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. 17618284 2007