|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease.
|
27162064 |
2016 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease.
|
23137822 |
2013 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The meta-analyses indicated the significant associations of two AGT polymorphisms (M235T, T174M) with CHD risk in the Chinese population.
|
22791700 |
2013 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Angiotensinogen gene M235T polymorphism and risk of coronary artery disease: a meta-analysis.
|
22842872 |
2012 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
There were significant interactions between sex and AGT1R 1166 C-allele (p = 0.008) and AGT M235T (p = 0.03) in models for CHD.
|
19327134 |
2009 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia.
|
18409009 |
2008 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The M235T polymorphism in the AGT gene and CHD risk: evidence of a Hardy-Weinberg equilibrium violation and publication bias in a meta-analysis.
|
18575631 |
2008 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggested an overall weak association between the M235T polymorphism and CHD risk.
|
17846284 |
2007 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In Slovak population, M235T is associated with increased blood pressure and D allele of ACE gene is associated with MI, chronic CHD and DCM, rather than with hypertension.
|
17579251 |
2007 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The angiotensinogen M235T variant was analyzed in 871 consecutive patients with clinically suspected coronary artery disease submitted to coronary angiography study.
|
16045904 |
2005 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The TT genotype of the AGT gene M235T polymorphism was associated with an increased risk of CHD and myocardial infarction only in smokers.
|
14502296 |
2003 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
M235T and T174M variants do not contribute to the increased risk of CHD or hypertension in the Indian population.
|
12938141 |
2003 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The angiotensinogen M235T polymorphism is positively associated with plasma angiotensinogen, hypertension, and coronary heart disease.
|
12040348 |
2002 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study shows that genetic variation of the AGT (M235T), but not the ACE (I/D), genotypes contributes to the presence of CHD independently of blood pressure profile in a subset of the Spanish population with a high prevalence of cardiovascular disease.
|
11345362 |
2001 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In 257 Dutch IDDM patients (188 with urinary albumin excretion (UAE) <30 mg/24 h), logistic regression analysis was used to study the relationships among, on the one hand, the insertion/deletion gene polymorphism of the angiotensin-converting enzyme gene (ACE-ID), the M235T gene polymorphism of the angiotensinogen gene (AGT-M235T), and the A1166C gene polymorphism of the angiotensin type 1 receptor gene (AT1-A1166C), and, on the other hand, UAE, retinopathy, hypertension, and coronary heart disease.
|
10862638 |
2000 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Polymorphism frequencies for angiotensin-I-converting enzyme insertion/deletion (ACE I/D), angiotensinogen M235T, and angiotensin-II type I receptor (AG2R) A1166C were determined in 112 patients with FH and 72 patients with polygenic hypercholesterolemia, of whom 26.7% and 41.6%, respectively, had established CHD.
|
11082147 |
2000 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
An interaction between both angiotensinogen gene polymorphisms on the extent of CHD or on the risk of non-fatal MI were not observed when the M allele of AGT T174M was combined either with the T allele or the TT genotype of M235T.
|
10488958 |
1999 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The significant relations observed between the AGT M235T variant, its protein product, and the cardiovascular disease phenotypes provide evidence for a possible role of elevated circulating AGT in the pathogenesis of coronary artery disease.
|
10097233 |
1999 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
This case-control study was initiated to investigate whether the ACEI/D and AGT M235T polymorphisms are associated with an increased risk for coronary heart disease (CHD) and MI.
|
9034401 |
1997 |
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
We found a correlation between the M235T molecular variant of AGT and the S128R variant of E-selectin to early severe CHD.
|
9020385 |
1997 |