|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The AGT (M268T) genotypes were distributed in IgAN as CC 61.9%, CT 34.8%, and TT 3.2%, while in controls CC 64.1%, CT 31.3%, and TT 4.6%.
|
26588355 |
2015 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
rs699 in the AGT gene and rs5186 in the ATR1 gene were not associated with the risk and clinical outcomes of IgAN.
|
26588355 |
2015 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, AGT M235T gene polymorphism may not be correlated with IgAN susceptibility in overall populations, Caucasians and Asians.
|
24344785 |
2014 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The angiotensin I-converting enzyme (ACE) gene insertion/deletion (I/D), the angiotensinogen (AGT) gene, M235T, the aldosterone synthase (CYP11B2) gene, C-344T, and the angiotensin II type 1 receptor (AT1R) gene, A1166C, have been shown to be associated with IgA nephropathy (IgAN) and its progression.
|
21163122 |
2010 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our results suggest that the AGT M235T polymorphism is associated with the progression of IgAN in Korean male patients.
|
19729965 |
2009 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our results suggest that angiotensinogen-M235T polymorphism is an important marker of progression in IgA nephropathy in Caucasian patients, especially when analyzed in combination with ACE-I/D polymorphism.
|
15031629 |
2004 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
The angiotensin I-converting enzyme (ACE) gene insertion/deletion (I/D), the angiotensinogen (AGT) gene, M235T, and the angiotensin II type 1 receptor (ATR) gene, A1166C, polymorphisms have been associated with IgA nephropathy (IgAN) and its progression.
|
15504143 |
2004 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study provides evidence that the M235T and A(-20)C genotype of AGT can influence the therapeutic efficacy of a RAS blockade on the renal survival in IgAN.
|
12911556 |
2003 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
To evaluate the role of AGT polymorphisms in the progression of IgA nephropathy (IgAN), we analyzed the association of A(-20)C and M235T polymorphisms with renal prognosis in histologically-proven IgAN patients using the Kaplan-Meier method and Cox proportional hazards regression model.
|
12164881 |
2002 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
We identified the M235T polymorphism of the angiotensinogen (AGT) gene, the I/D polymorphisms of the angiotensin-converting enzyme (ACE) gene, and the A1166C polymorphism of the angiotensin II type 1 receptor gene in 95 Japanese children with IgA nephropathy and 99 healthy Japanese adults.
|
11354780 |
2001 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
Deletion/insertion polymorphism (D/I) of the angiotensin I converting enzyme gene, M235T polymorphism (T/M) of the angiotensinogen gene and A1166C polymorphism (C/A) of the angiotensin II type 1 receptor gene were determined in 274 Caucasian men with biopsy-proven IgAN (n = 86, 112, and 76 in stages 1, 2, and 3, respectively).
|
11053482 |
2000 |
|
IGA Glomerulonephritis
|
|
0.100 |
GeneticVariation
|
BEFREE |
We examined whether the M235T polymorphism of the angiotensinogen (AGT) gene, the insertion/deletion polymorphism of the angiotensin-converting enzyme (ACE) gene, and the A1166--> C polymorphism of the angiotensin II type 1 receptor gene may be associated with disease progression in 168 Caucasian patients with IgA nephropathy.
|
9259580 |
1997 |