rs699, AGT

N. diseases: 134
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE Simultaneous Genotyping of the rs4762 and rs699 Polymorphisms in Angiotensinogen Gene and Correlation with Iranian CAD Patients with Novel Hexa-primer ARMS-PCR. 28828324 2017
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease. 27162064 2016
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease. 23137822 2013
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE AGT gene polymorphisms (M235T, T174M) are associated with coronary heart disease in a Chinese population. 22791700 2013
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE The current meta-analysis suggests that the M235T</span> polymorphism is associated to an increased risk of CAD. 22842872 2012
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE The AGT M235T polymorphism associates with AMI risk and influences CAD severity. 20663844 2011
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE Co-existing angiotensinogen M235T AGT polymorphism and two other common polymorphisms of the RAS genes are related to adverse events in patients with CAD. 21769789 2011
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE The frequency of eNOS TT allele of M</span>235T variant was significantly higher in patients with CAD (20% vs 6%). 20547537 2011
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE In conclusion, our results suggest that a significantly higher risk of CAD was associated with the Ins/Del, the M235T, and T174M polymorphisms; other environmental variables such as body mass index; and biochemical variables such as cholesterol. 20854100 2010
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE No association between AGT M235T, AGT T174M, ACE I/D and AT(1) receptor A1166C polymorphisms and CAD was observed. 20223792 2010
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia. 18409009 2008
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE The data hereby provide further support for the association between angiotensinogen M235T polymorphism and CAD severity independently of other cardiovascular risk factors. 16045904 2005
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE The angiotensinogen M235T polymorphism is positively associated with plasma angiotensinogen, hypertension, and coronary heart disease. 12040348 2002
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE AGT M235T and ATR A1166C allele and genotype frequencies were similar between CAD and CAD-free patients. 11393670 2001
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE Association of angiotensinogen M235T and A(-6)G gene polymorphisms with coronary heart disease with independence of essential hypertension: the PROCAGENE study. Prospective Cardiac Gene. 11345362 2001
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE In 257 Dutch IDDM patients (188 with urinary albumin excretion (UAE) <30 mg/24 h), logistic regression analysis was used to study the relationships among, on the one hand, the insertion/deletion gene polymorphism of the angiotensin-converting enzyme gene (ACE-ID), the M235T gene polymorphism of the angiotensinogen gene (AGT-M235T), and the A1166C gene polymorphism of the angiotensin type 1 receptor gene (AT1-A1166C), and, on the other hand, UAE, retinopathy, hypertension, and coronary heart disease. 10862638 2000
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE The significant relations observed between the AGT M235T variant, its protein product, and the cardiovascular disease phenotypes provide evidence for a possible role of elevated circulating AGT in the pathogenesis of coronary artery disease. 10097233 1999
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE These associations did not disappear when the analyses were corrected for multiple comparisons for other gene polymorphisms (ACE I/D gene variation, angiotensinogen T174M and M235T gene polymorphisms, AT1 receptor gene variation, phox C242T gene polymorphism, paraoxonase PON54 and PON191 gene variations) (2p = 0.01 in MLR for the presence of CAD; 2p = 0.039 in multiple regression for the extent of CAD). 10488959 1999
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.800 GeneticVariation BEFREE Results indicate that the M235T and T174M variants of the angiotensinogen gene are not associated with CAD in Japanese men. 9313606 1997