Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
Simultaneous Genotyping of the rs4762 and rs699 Polymorphisms in Angiotensinogen Gene and Correlation with Iranian CAD Patients with Novel Hexa-primer ARMS-PCR.
|
28828324 |
2017 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease.
|
27162064 |
2016 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease.
|
23137822 |
2013 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
AGT gene polymorphisms (M235T, T174M) are associated with coronary heart disease in a Chinese population.
|
22791700 |
2013 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The current meta-analysis suggests that the M235T</span> polymorphism is associated to an increased risk of CAD.
|
22842872 |
2012 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The AGT M235T polymorphism associates with AMI risk and influences CAD severity.
|
20663844 |
2011 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
Co-existing angiotensinogen M235T AGT polymorphism and two other common polymorphisms of the RAS genes are related to adverse events in patients with CAD.
|
21769789 |
2011 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The frequency of eNOS TT allele of M</span>235T variant was significantly higher in patients with CAD (20% vs 6%).
|
20547537 |
2011 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that a significantly higher risk of CAD was associated with the Ins/Del, the M235T, and T174M polymorphisms; other environmental variables such as body mass index; and biochemical variables such as cholesterol.
|
20854100 |
2010 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
No association between AGT M235T, AGT T174M, ACE I/D and AT(1) receptor A1166C polymorphisms and CAD was observed.
|
20223792 |
2010 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia.
|
18409009 |
2008 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The data hereby provide further support for the association between angiotensinogen M235T polymorphism and CAD severity independently of other cardiovascular risk factors.
|
16045904 |
2005 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The angiotensinogen M235T polymorphism is positively associated with plasma angiotensinogen, hypertension, and coronary heart disease.
|
12040348 |
2002 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
AGT M235T and ATR A1166C allele and genotype frequencies were similar between CAD and CAD-free patients.
|
11393670 |
2001 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
Association of angiotensinogen M235T and A(-6)G gene polymorphisms with coronary heart disease with independence of essential hypertension: the PROCAGENE study. Prospective Cardiac Gene.
|
11345362 |
2001 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
In 257 Dutch IDDM patients (188 with urinary albumin excretion (UAE) <30 mg/24 h), logistic regression analysis was used to study the relationships among, on the one hand, the insertion/deletion gene polymorphism of the angiotensin-converting enzyme gene (ACE-ID), the M235T gene polymorphism of the angiotensinogen gene (AGT-M235T), and the A1166C gene polymorphism of the angiotensin type 1 receptor gene (AT1-A1166C), and, on the other hand, UAE, retinopathy, hypertension, and coronary heart disease.
|
10862638 |
2000 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
The significant relations observed between the AGT M235T variant, its protein product, and the cardiovascular disease phenotypes provide evidence for a possible role of elevated circulating AGT in the pathogenesis of coronary artery disease.
|
10097233 |
1999 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
These associations did not disappear when the analyses were corrected for multiple comparisons for other gene polymorphisms (ACE I/D gene variation, angiotensinogen T174M and M235T gene polymorphisms, AT1 receptor gene variation, phox C242T gene polymorphism, paraoxonase PON54 and PON191 gene variations) (2p = 0.01 in MLR for the presence of CAD; 2p = 0.039 in multiple regression for the extent of CAD).
|
10488959 |
1999 |
Coronary Artery Disease
|
|
0.800 |
GeneticVariation
|
BEFREE |
Results indicate that the M235T and T174M variants of the angiotensinogen gene are not associated with CAD in Japanese men.
|
9313606 |
1997 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
Mean blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.
|
27618448 |
2016 |
Blood Pressure
|
|
0.700 |
GeneticVariation
|
GWASDB |
Blood pressure loci identified with a gene-centric array.
|
22100073 |
2011 |
Cardiovascular Diseases
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results of a genome-wide association study (GWAS) showed that two functional single-nucleotide polymorphisms (SNPs; rs699A>G and rs5050T>G) in the angiotensinogen (AGT) gene were related to cardiovascular disease susceptibility.
|
30719178 |
2019 |
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
We did not observe associations between hypertension and rs1799752 (<i>P</i>=0.422), rs699 (<i>P</i>=0.36), rs5186 (<i>P</i>=0.49), and rs1799998 (<i>P</i>=0.71).
|
31511791 |
2019 |