rs7229639, SMAD7

N. diseases: 13
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Digestive System Disorders
CUI: C0012242
Disease: Digestive System Disorders
0.010 GeneticVariation BEFREE Genome-wide association studies (GWAS) have identified three loci at 18q21 (rs4939827, rs7240004, and rs7229639), which maps to SMAD7 loci, were associated with risk of diseases of the digestive system. 26989026 2016
Adenoma of large intestine
CUI: C1302401
Disease: Adenoma of large intestine
0.010 GeneticVariation BEFREE Besides, seven SNPs (rs10808555, rs7014346, rs7837328, rs704017, rs11196172, rs4779584, and rs7229639) were significantly associated with CRC, and another one SNP rs11903757 was over-represented in CRA compared with controls. 27769063 2016
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.820 GeneticVariation BEFREE Besides, seven SNPs (rs10808555, rs7014346, rs7837328, rs704017, rs11196172, rs4779584, and rs7229639) were significantly associated with CRC, and another one SNP rs11903757 was over-represented in CRA compared with controls. 27769063 2016