rs73885319, APOL1

N. diseases: 6
Disease: Kidney Failure, Chronic ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Kidney Failure, Chronic
CUI: C0022661
Disease: Kidney Failure, Chronic
0.720 GeneticVariation GWASCAT Several variants at the <i>APOL1</i> locus were associated with ESKD including the <i>APOL1</i> G1 rs73885319 (<i>p</i> = 1.2 × 10<sup>-9</sup>). 31178898 2019
Kidney Failure, Chronic
CUI: C0022661
Disease: Kidney Failure, Chronic
0.720 GeneticVariation BEFREE Several variants at the <i>APOL1</i> locus were associated with ESKD including the <i>APOL1</i> G1 rs73885319 (<i>p</i> = 1.2 × 10<sup>-9</sup>). 31178898 2019
Kidney Failure, Chronic
CUI: C0022661
Disease: Kidney Failure, Chronic
0.720 GeneticVariation BEFREE We use recently released sequences from the 1000 Genomes Project to identify two western African-specific missense mutations (S342G and I384M) in the neighboring APOL1 gene, and demonstrate that these are more strongly associated with ESKD than previously reported MYH9 variants. 20635188 2010