rs744166, STAT3

N. diseases: 22
Disease: Ulcerative Colitis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.030 GeneticVariation BEFREE This meta-analysis indicates that carriers of the STAT3 rs744166 'A' allele have a significantly greater risk of CD and UC, especially among Caucasians. 25286337 2014
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.030 GeneticVariation BEFREE Our data confirm the association between JAK2 rs10758669 (p = 0.026, OR = 1.25, 95% CI = 1.04-1.50) and STAT3 rs744166 (p = 0.04, OR = 0.83, 95% CI = 0.688-0.998) with CD, but not UC. 22065112 2012
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.030 GeneticVariation BEFREE We could confirm the susceptibility of STAT3 rs744166 TT homozygotes for UC (OR: 1.483, 95% CI: 1.103-1.992, P = 0.009). 22269120 2012