rs7483, GSTM3;GSTM5

N. diseases: 11
Disease: Hormone refractory prostate cancer ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hormone refractory prostate cancer
CUI: C1328504
Disease: Hormone refractory prostate cancer
0.010 GeneticVariation BEFREE In metastatic prostate cancer, the AG/GG allele in GSTM3 rs7483</span> and CT/TT allele in CAT rs564250 were associated with a significantly lower risk of progression to CRPC and all-cause death compared with homozygotes of the major AA allele (hazard ratio [HR]; [95% confidence interval (CI)], 0.55 [0.34-0.86], P = 0.0086) and CC allele (HR; [95% CI], 0.48 [0.24-0.88], P = 0.016), respectively. 27993795 2017